Preparation of o-bromobenzophenone derivatives from lithium diarylcuprate(I) reagents
Articles > Article · 2000
Authors: Selhan Karag�z, Demet ASTLEY, Stephen T. Astley
Applied Organometallic Chemistry, International, WoS, 2000, vol 14, pp 341-344
DOI: 10.1002/1099-0739(200007)14:7<341::aid-aoc5>3.0.co;2-m
Summary
The reaction of lithium diarylcuprate(I) reagents with o-bromobenzoyl chloride has been investigated. In general, the reaction proceeds well to give synthetically useful o-bromobenzophenone derivatives as the major product. It is suggested that a minor substituent effect, whereby diarylcuprate reagents containing an ortho or meta substituent react more favourably, may be attributed to small changes in the structure of the organometallic reagent. Copyright © 2000 John Wiley & Sons, Ltd.