N-acetylcysteine in patients with COPD exacerbations associated with increased sputum
Articles > Article · 2015
Authors: ZEYNEP AYFER AYTEMUR, Aysegul Baysak, Ozer OZDEMIR, Timur KÖSE, Abdullah SAYINER
Wiener klinische Wochenschrift, Journal Indexed in SCI Expanded, International, WoS, 2015, vol 127, pp 256-261
DOI: 10.1007/s00508-014-0692-4
Summary
Background N-acetylcysteine (NAC) has been shown not to alter the clinical outcome in chronic obstructive pulmonary disease (COPD) exacerbations. However, NAC may improve symptoms through its mucolytic effect in the subgroup of patients with increased sputum production. The aims of this study were to determine whether NAC improves symptoms and pulmonary function in patients with COPD exacerbation and increased sputum production.