Atorvastatin improves peritoneal sclerosis induced by hypertonic PD solution in rats
Makaleler > Tam Makale · 2005
Yazarlar: Soner DUMAN, Sait ŞEN, Eser YILDIRIM SÖZMEN, DG OREOPOULOS
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2005, cilt 28, ss 170-176
Özet
Background: Peritoneal sclerosis is a complication of peritoneal dialysis and results in ultrafiltration failure. It is related to chronic peritoneal injury due to dialysis solution content and recurrent peritonitis. Statins have anti-inflammatory properties which may be of value in modulating responses to injury. We evaluated the capacity of atorvastatin to modify peritoneal alterations secondary to hypertonic glucose.