Whole-genome gene expression analysis in urine samples of patients with prostate cancer and benign prostate hyperplasia
Makaleler > Tam Makale · 2017
Yazarlar: Taha Resid Ozdemir, Adnan ŞİMŞİR, HÜSEYİN ONAY, İbrahim Kadri CÜREKLİBATIR, Feriştah Ferda ÖZKINAY, Haluk AKIN
Urologic Oncology: Seminars and Original Investigations, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2017, cilt 35, ss 607.e15-607.e24
DOI: 10.1016/j.urolonc.2017.05.020
Özet
Objective: There is an urgent need to find new biomarkers with higher specificity and sensitivity for using early detection of prostate cancer (PrCa) and reducing recurrent unnecessary biopsy rates, psychological and physical stress on the patient, and costs. Being noninvasive, urine-based tests might be suitable in routine practice. The aim of this study was to report the first whole-genome gene expression analysis in urine samples, as noninvasive method, that were obtained from PrCa, benign prostate hyperplasia (BPH), and control groups by using the microarray system from Turkey, to our knowledge.