The Relationship Between Noise-Induced Occupational Sensorineural Hearing Loss and Platelet Panel: A Retrospective Study
Makaleler > Tam Makale · 2023
Yazarlar: Yusuf Samir Hasanlı, Meral Türk
Journal of Ankara University Faculty of Medicine, Uluslararası, 2023, cilt 76, ss 116-121
DOI: 10.4274/atfm.galenos.2023.49344
Özet
Objectives: There are various risk factors such as age, genetics, smoking, hypertension, diabetes mellitus, and vascular diseases that affect noiseinduced Occupational Sensorineural Hearing Loss (OSNHL).In addition to nerve damage, pathology may occur in the vascular and hematological structure of the cochlear system in sensorineural hearing loss.For this reason, we wanted to evaluate the relationship between platelet panel parameters and hearing loss.Materials and Methods: Socio-demographic characteristics, audiometry results, platelet parameters, physical examination and admission complaints were collected in the data package by retrospectively scanning patient files.The patients were evaluated for the presence of OSNHL.Subgroup analysis was performed.Since all patients work in similar industrial environments, it was assumed that there would be a risk of noise in all of them.Results: The mean age of the patients was 40.0±8.3(302 patients).Patients with OSNHL were older than those without hearing loss (43.5±8.0;36.2±6.9 p<0.001).The ratio of male and female patients with OSNHL was 146/11, and 139/6 in those without hearing loss.Platelet count and plateletcrit values of patients with OSNHL were found to be higher and statistically significant (275.7±62.4,245.1±42.0p<0.001, 0.28±0.06;0.25±0.04p<0.001, respectively).There was no difference between mean platelet volume (MPV) values (10.4±0.8;10.3±0.8 p=0.654).There was no significant correlation between age, smoking and platelet panel in patients with and without hearing loss (Pearson's correlation analysis).Receiver operating characteristic analysis of thrombocyte counts, plateletcrit and MPV values of patients with hearing loss was performed [respectively; area under the curve (AUC)=0.64 (0.57-0.70 p<0.001),AUC=0.65 (0.58-0.71 p<0.001),AUC=0.52 (0.45-0.58 p=0.522)].Conclusion: Platelet count and plateletcrit values are higher in patients with OSNHL than those without hearing loss, regardless of age and smoking.