Biosensors of in vitro detection of cancer and bacterial cells
Book chapter > Chapter Other Book ยท 2016
Authors: Seda Nur Topkaya, Mostafa Azimzadeh
Nanobiosensors for Personalized and Onsite Biomedical Diagnosis, Chapter Other Book, Institution of Engineering and Technology, B, International, 2016, pp 73-94, ,
DOI: 10.1049/pbhe001e_ch5
Summary
This chapter describes some representative examples of in vitro detection of cancer and bacterial cells within the scope of biosensor systems. In cancer cell detection, priority is given to aptamers-based biosensors and the detailed information about the detection of cancer cells with the help of aptamers is explained. In the case of bacterial cells detection, electrochemical and optical biosensors that produce an electronic or optical signal proportional to the specific interaction between the target and the recognition molecule immobilized on the biosensor is elaborately exampled. In addition, microfluidics, LOC and paper-based detection systems for in vitro bacterial cells detection are emphasized in the chapter.