Hippocampal shape alterations in healthy young women with familial risk for unipolar depression
Articles > Article · 2018
Authors: Ece DURMUŞOĞLU, Onur UĞURLU, Sebnem AKAN, Fatma ŞİMŞEK, Gozde KIZILATEŞ, Ömer KİTİŞ, Burcu Aksoy OZKUL, Mehmet Çağdaş EKER, Kerry L. Coburn, Ali Saffet GÖNÜL
Comprehensive Psychiatry, Journal Indexed in SCI Expanded, International, WoS, 2018, vol 82, pp 7-13
DOI: 10.1016/j.comppsych.2018.01.004
Summary
Background: Although reduced hippocampal volume (HCV) is a common finding in depression, it is unclear whether the structural alterations leading to reduction of HCV are pre-existing risk factors before the onset of clinical symptoms or a cumulative process that begins with the onset of clinical symptoms. The aim of the present study was to understand the anatomical status of the hippocampus prior to the clinical symptoms in subjects with high familial risk for depression.