Suzuki–Miyaura Reaction of Unactivated Aryl Chlorides Using Benzimidazol‐2‐Ylidene Ligands
Makaleler > Tam Makale · 2004
Yazarlar: İsmail Özdemir, Yetkin Gök, Nevin Gürbüz, Engin Çetinkaya, Bekir Çetinkaya
Synthetic Communications, Uluslararası, Wos, 2004, cilt 34, ss 4135-4144
Özet
Four functionalized bis(benzimidazolium) salts (2a–d) have been prepared and characterized by conventional spectroscopic methods and elemental analyses. A highly effective, easy to handle, and environmentally bengin process for palladium‐mediated Suzuki cross‐coupling was developed. The in situ prepared three‐component system Pd(OAc)2/bis(benzimidazolium) bromides (2a–d) and Cs2CO3 catalyzes quantitatively the Suzuki cross‐coupling of deactivated aryl chloride in aqueous media.