Do salivary and serum collagenases have a role in an association between obstructive sleep apnea syndrome and periodontal disease? A preliminary case–control study
Articles > Article · 2014
Authors: Nejat NİZAM, Özen KAÇMAZ BAŞOĞLU, Meltem TAŞBAKAN, Anna Holthofer, Taina Teruahartiala, Timo Sorsa, Nurcan Buduneli
Archives of Oral Biology, Journal Indexed in SCI Expanded, International, WoS, 2014, vol 60, pp 134-143
DOI: 10.1016/j.archoralbio.2014.09.006
Summary
Objectives: Despite increasing evidence for an association of obstructive sleep apnea syndrome (OSAS) and periodontal disease, the pathophysiological linking mechanisms remain unclear. This study aims to evaluate the salivary and serum matrix metalloproteinase-2, -8, -9 (MMP-2, -8, -9), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), myeloperoxidase (MPO), neutrophil elastase (NE), neutrophil gelatinase-associated lipocalin (NGAL), as well as degree of activation of MMP-2, -9 of patients with and without OSAS.