Cisplatin ototoxicity in children: risk factors and its relationship with polymorphisms of DNA repair genes ERCC1, ERCC2, and XRCC1

Articles > Article · 2019

Authors: C Turan, Mehmet KANTAR, Ç Aktan, Buket KOSOVA, Mehmet Nurullah ORMAN, C Bilgen, T Kirazlı

CANCER CHEMOTHERAPY AND PHARMACOLOGY, Journal Indexed in SCI Expanded, International, 2019, vol 84, pp 1333-1338

DOI: 10.1007/s00280-019-03968-2

Summary

Purpose We aimed to investigate the cisplatin-related hearing toxicity and its possible relationship with polymorphic variants in DNA repair genes, ERCC1, ERCC2, and XRCC1.

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