Microalgae: From culture medium to medicine
Makaleler > Tam Makale · 2013
Yazarlar: M Sensoy, Z Dogan, Meltem DALAY, Zeliha DEMİREL, I Saracoglu
Planta Medica, Uluslararası, Wos, 2013, cilt 79
Özet
Microalgae have become an important commercial source of many valuable compounds, such as carotenoids, lipids, proteins, polysaccharides, used in pharmaceutical and industrial purposes. As a result of this rich composition, microalgae-derived products consumed by people for many reasons; for health improvement, for cosmetic use and as food supplements. Also, they have been used as feed ingredient for animals. Spirulina platensis, Dunaliella salina, Haematococcus pluvialis and Chlorella sp. are very well-known microalgae species which are used in pharmacologic field all around the world. In general, microalgae have hepatoprotective, antimicrobial, antioxidant, immunstimulant activities; and also they have colouring properties as natural dyes for medicines, foods, cosmetics and analitical applications (1). In the present study, microalgae samples were collected from different geothermal water supplies in Afyonkarahisar, Turkey. At the first glance, cyanobacteria, diatoms and some coccus microalgae strains were defined. These strains were isolated as a single strain and cultured in their own geothermal water, at 30 ± 2 0 C, 24h light period of 20µmol m -2 s -1 . Biomass concentration was determined with spectrophotometric method, and simultaneously controlled chlorophyll-α and dry mass analysis. An HPLC method was developed to discern the variety and content of microalgae carotenoids. Some HPLC standarts, beta-carotene, astaxanthin and canthaxanthin were purchased and lutein, violaxanthin and neoxanthin were isolated from spinach (2). DPPH (1,1 – diphenyl-2-picrylhydrazyl), SO (superoxide) and NO (nitric oxide) radical scavenging activity methods were used to highlight the antioxidant potential of the samples. In conclusion, some microalgae can also be cultured in geothermal water as a source of bioactive compounds for medicinal and nutritional use. References: [1] Mendes, R. et al. (2003) Inorg Chim Acta, 356, 328. [2] Kao, T.H. et al. (2012)J Pharm Biomed Anal, 66, 144.