Extraction and characterization of valuable compounds from chicken sternal cartilage: Type II collagen and chondroitin sulfate
Makaleler > Tam Makale · 2025
Yazarlar: Ozge Ata, Neslihan Bozdogan, Ceren Evrim Mataraci, Seher KUMCUOĞLU, Sibel Kaya Bayram, Sebnem Tavman
FOOD CHEMISTRY, SCI İndekslerine Giren Dergi, Uluslararası, Wos, 2025, cilt 462, ss 1-9
DOI: 10.1016/j.foodchem.2024.141023
Özet
Type II collagen (Col II) and chondroitin sulfate (CS) are the main macromolecules in the extracellular matrix. This study investigated the characteristics of Col II and CS obtained from chicken sternal cartilage (CSC) via enzymatic hydrolysis for various treatment times. For Col II and CS, the highest efficiency of enzymatic hydrolysis was achieved after 24 and 6 h of treatment, respectively. The average molecular weights were alpha 1 chain-130 kDa, beta chain-270 kDa for Col II, and 80.27 kDa for CS. Fourier transform infrared spectroscopy revealed that the Col II samples maintained their triple-helical structure and that the predominant type of CS was chondroitin-4-sulfate. Scanning electron microscopy revealed that the Col II and CS samples possessed fibrillar and clustered structures, respectively. This study suggests that collagen and CS obtained from CSC can be used as promising molecules for application in food and pharmaceutical industries.