DIURETIC EFFECT OF FRUSEMIDE IN PATIENTS WITH NEPHROTIC SYNDROME - IS IT POTENTIATED BY INTRAVENOUS ALBUMIN
Makaleler > Tam Makale · 1995
Yazarlar: F AKCICEK, T YALNIZ, ALİ BAŞCI, Ercan OK, EJD MEES
BRITISH MEDICAL JOURNAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 1995, cilt 310, ss 162-163
Özet
We investigated the claim that infusion of albumin potentiates the diuretic effect of frusemide in patients with the nephrotic syndrome.1 We selected 12 inpatients with the nephrotic syndrome according to two criteria: (a) failure to lose weight after bed rest and a 40 mmol sodium diet and (b) presence of minimal lesions or a well preserved glomerular histology on renal biopsy. We gave each patient three treatments randomly from 8 am to noon, at intervals of at least two days—infusion of albumin 0.5 g/kg given as a 20% solution for four hours; infusion of frusemide 60 mg bolus followed by 40 mg/h for four hours; and a combined treatment of both types of infusion. We collected urine on the treatment days from 8 am to 2 pm and …