1,4,5,6-Tetrahydropyrimidinium Halides Ligands for Suzuki-Miyaura Cross-Coupling of Unactivated Aryl Chlorides
Makaleler > Tam Makale · 2005
Yazarlar: Ismail Özdemir, Bülent Alıcı, Nevin Gürbüz, Engin Çetinkaya, Bekir Çetinkaya
HETEROCYCLES, Uluslararası, Wos, 2005, cilt 65, ss 1439-1439
DOI: 10.3987/com-05-10363
Özet
Four functionalized bis (1,4,5,6-tetrahyropyrimidinium) salts (2a-d) have been prepared and characterized by conventional spectroscopic methods and elemental analyses.A highly effective, easy to handle and environmentally benign process for palladium mediated Suzuki cross-coupling was developed.The in situ prepared three component system Pd(OAc) 2 / bis(1,4,5,6tetrahyropyrimidinium) bromides (2a-d) and Cs 2 CO 3 catalyses quantitatively the Suzuki cross-coupling of deactivated aryl chloride.