Lipoprotein-associated phospholipase A<sub>2</sub>: a new marker to determine cardiovascular risk in hypercholesterolemic dyslipidaemic children.

Articles > Article · 2016

Authors: Belkız Öngen, Sema KALKAN UÇAR, Reşit Ertürk LEVENT, Elif AZARSIZ, Turan Koloğlu, Mahmut ÇOKER, Eser YILDIRIM SÖZMEN, Ferhan GİRGİN SAĞIN

ANNALS OF CLINICAL BIOCHEMISTRY, Journal Indexed in SCI Expanded, International, 2016, vol 54, pp 539-547

DOI: 10.1177/0004563216671338

Summary

Background Inflammation and hypercholesterolaemia contribute to atherosclerotic changes which can start in childhood. Children with hyperlipidaemias are at high risk for early coronary atherosclerosis. This study evaluates the relationship between lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), carotid intima-media thickness (CIMT) and flow-mediated dilatation in hypercholesterolaemic dyslipidaemic children.

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