SP611DOES INTERDIALYTIC WEIGHT GAIN EFFECT HEMOGLOBIN VARIABILITY
Bildiriler > Özet Bildiri
Yazarlar: Cenk Gokalp, Ender Hür, Merve Gülşah Ulusoy, Elif Duman, Hüseyin Taşkın, Selahattin Bıçak, Özge Timur, Neşe Büyükoğlan, Necati Özkan, Ertugrul Cakır, Gürcan Yurtman, İlhan Akgüngör, Zeki Malkoç, Soner DUMAN
Nephrology Dialysis Transplantation, , , Uluslararası, Özet Bildiri, Wos, cilt 32, ss iii340-iii340
Özet
INTRODUCTION AND AIMS: There are studies showing, hemoglobin (Hgb) variability increase mortality in hemodialysis (HD) patients. As volume changes known to have an effect on Hgb concentration, volume status must be taken into account on Hgb variability definition. METHODS: Present study 552 prevalent HD patients of 62.5% men, being treated at five HD centers in Aegean region with the age of 64±15 years were included. In between 2013-2014 baseline demographic, every 6 months of laboratory, and monthly all therapy sessions data were prospectively followed unattended. "Adjusted Hbg = Hgb * HD input kg / HD output kg" formula used for calculation. Hgb (g/dl) may be lower (L): <11, moderate (M): 11-12, high (H):> 12, the stable group LL, MM, HH; variable groups: LM, LH and MH are classified. Pearson correlation test, Student's t test and nonparametric tests (Kruskal Wallis, Man Whitney U test) were used for statistical evaluation. P <0.05 was considered as significant. RESULTS: There are significant shifts in Hgb variability between groups after Hgb corrections. In variable groups, after correction 83.9% LH, 75.9% HM, 53.9% LM of patients remained already in their group. Stable groups, 76% HH, 33.4% MM, 77.1% LL of patients remaining stuck in their group of the remaining shifted to other groups. Many patients thought to have been in Hgb variability groups in fact changed to stable group if volume status taken into account and vice versa is also valid but in much less patients. Interdiyalitik weight gain (IDWG) at weekday, weekend and IDWG/DW % at weekend were less in Hgb variability group compared to stable group but non significant at weekday. According to corrected hemoglobin it decreased but weekday IDWG/DW% gained significant differences (Table). In Hgb variability group IDWG/DW % 3.16±1.1 was more than stability group 3.11±1.3 unsignificantly according to adjusted Hgb. CONCLUSIONS: In HD patients IDWG/DW % must be used instead of IDWG for hypervolemia. Hemoglobin variability diagnosis needs the adjustment according to volume status. Volume status of Hgb variability group is worse and increased mortality of patients must not be considered without it.