Different clinical courses with the same findings: two cases of paroxysmal nocturnal hemoglobinuria presenting with thrombocytopenia

Articles > Article · 2021

Authors: Volkan Karakus, Egemen Kaya, Yelda Dere, Fahri ŞAHİN

Italian Journal of Medicine, Journal Indexed in SCI Expanded, International, Scopus, 2021, vol 15, pp 188-190

DOI: 10.4081/itjm.2021.1319

Summary

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disease that manifests with chronic intravascular hemolysis, thrombosis, and bone marrow failure. Various degrees of cytopenias accompany the disease. Although laboratory and clinical findings are similar, the disease may show different courses and require different treatments. Herein, we report two different courses of PNH with similar clinical and laboratory findings.

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