Effect of non-surgical periodontal treatment on gingival crevicular fluid hypoxia inducible factor-1 alpha, vascular endothelial growth factor and tumour necrosis factor- alpha levels in generalized aggressive periodontitis patients.
Makaleler > Tam Makale · 2020
Yazarlar: B Afacan, Yücel Keleş, Ç Paşali, İlhan Atmaca, Timur KÖSE, Gülnur EMİNGİL
JOURNAL OF PERIODONTOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2020, cilt 91, ss 1495-1502
DOI: 10.1002/jper.19-0521
Özet
Background Hypoxia-inducible angiogenic pathway involving hypoxia inducible factor-1 alpha (HIF-1 alpha), vascular endothelial growth factor (VEGF) and tumor necrosis factor-alpha (TNF-alpha) may regulate several biological processes related to inflammation. The present study aimed to assess the effect of non-surgical periodontal treatment on gingival crevicular fluid (GCF) HIF-1 alpha, VEGF, and TNF-alpha levels in generalized aggressive periodontitis (G-AgP).