Reduced left uncinate fasciculus fractional anisotropy in deficit schizophrenia but not in non-deficit schizophrenia

Articles > Article · 2012

Authors: Ömer KİTİŞ, Ozgun ÖZALAY, E. Burcak Zengin, Damla HAZNEDAROĞLU, Mehmet Çağdaş EKER, Dilek YALVAÇ, Kaya OĞUZ, Kerry Coburn, Ali Saffet GÖNÜL

PSYCHIATRY AND CLINICAL NEUROSCIENCES, Journal Indexed in SCI Expanded, International, 2012, vol 66, pp 34-43

DOI: 10.1111/j.1440-1819.2011.02293.x

Summary

Aims: Schizophrenia is a psychiatric disorder manifesting with heterogeneous symptom clusters and clinical presentations. The deficit syndrome is the condition defined by the existence of primarily negative symptoms, and patients with the deficit syndrome differ from non-deficit patients on measures of brain structure and function. In the current study, by using diffusion tensor imaging (DTI), we investigated the frontotemporal connectivity that is hypothesized to differ between deficit and non-deficit schizophrenia.

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