Anti toxic effect of broccoli extract on stannous dichloride toxicity
Makaleler > Tam Makale · 2012
Yazarlar: Betul ÇEKİÇ, Fazilet Zumrut Biber MUFTULER, Ayfer YURT KILÇAR, Necati GUNAY, Serhan SAKARYA, Perihan ÜNAK
ACTA CIRURGICA BRASILEIRA, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2012, cilt 27, ss 606-610
DOI: 10.1590/s0102-86502012000900003
Özet
PURPOSE: Since Technetium-99m (Tc-99m) has favorable physical and chemical characteristics, it is widely used radioisotope in Nuclear Medicine. However, stannous dichloride (SnCl2) has been widely used as a reducing agent in labeling procedure of pharmaceutical with radionuclide, it has been realized that SnCl2 have genotoxic and cytotoxic effects on biological systems. In previous studies, it has been shown that some herbal extract can reduce genotoxic and cytotoxic effects of SnCl2. In the present study, it is aimed to evaluate the effect of the broccoli extract on the survival of E. coli ATCC 25922 strain against to toxic effects of SnCl2.