Evaluating impulse oscillometry for respiratory assessment and management in children with neuromuscular diseases
Bildiriler > Özet Bildiri
Yazarlar: ECE OCAK, Gökçen Kartal Özturk, Yavuz Ataş, Ece Haliz, Bahar Girgin Dindar, Fevziye Çoksüer, Meral Barlık, Mehmet Mustafa ÖZASLAN, Atacan Öğütçü, Seda KANMAZ, Sanem KESKİN YILMAZ, Esen Demir, Hasan TEKGÜL, Figen GÜLEN
Paediatric respiratory physiology and diagnostic testing, , , Uluslararası, Özet Bildiri, ss PA554-PA554
DOI: 10.1183/13993003.congress-2025.pa554
Özet
An impulse oscillometry system (IOS) is a non-invasive, easily accessible, and well-tolerated respiratory function test. Due to the difficulty of spirometry's application, we aimed to evaluate its usability in the diagnostic modalities of pulmonary outcomes in children with neuromuscular disease. In this retrospective cross-sectional study, we measured the respiratory functions with IOS and spirometry and noted the clinical characteristics [the Pediatric Sleep Questionnaire (PSQ) scores and the motor functional scores (Brooke and Vignos functional scales)]. Respiratory impairment was classified as severe (FVC<50%) and non-severe (FVC≥50%). There was a significant correlation between raw values of spirometry and IOS parameters of the study group (n=59) (p<0.001). The PSQ scores were negatively correlated with X5 and X10 and positively correlated with R5 and fRES (p<0.05). Patients with severe restriction had lower X10 than the non-severe group (p<0.05). The values of X10 were used to predict severe lung restriction: sensitivity (71.4%) and specificity (68%) (95% CI, 0.556-0.953). We defined predictivity values of the IOS parameters with a relationship with the motor functional scale and PSQ scores. IOS might be an alternative method for evaluating respiratory impairment in children with neuromuscular disorders. Figure 1 Scatter plot graphics between IOS parameters (y-axis) and FVC (x-axis) erj;66/suppl_69/PA554/F1 F1 F1