The diagnostic value of multimodal evoked potentials in the determination of subclinical neurological involvement of Wilson's disease
Articles > Article · 2012
Authors: Cigdem ECEVIT, Funda ÇETİN, Figen GÖKÇAY, Neşe ÇELEBİSOY, Masallah BARAN, Rasit Vural YAGCI
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Journal Indexed in SCI Expanded, International, 2012, vol 24, pp 627-632
DOI: 10.1097/meg.0b013e3283526f81
Summary
Aims Wilson's disease (WD) is a progressive degeneration of hepatolenticular tissue caused by excessive tissue-damaging copper accumulation and in which liver involvement most frequently presents in childhood. Neurological signs also accompany liver disease with time. However, subclinical neurological involvement may occur earlier and diagnostic methods that reveal this subclinical involvement are not well established. The aim of the current study is to assess the subclinical neurological involvement by using multimodality evoked potential (EP) measurements and to explore the relationship between neurological disease and the severity of liver damage.