Mg/Zn COMPOSITES PRODUCED BY MECHANICAL ALLOYING AND HOT PRESSING AND IN-VITRO BIODEGRADATION
Makaleler > Tam Makale · 2018
Yazarlar: Rasim İPEK, SERAP CESUR, Simay Erdibil
Usak University Journal of Engineering Sciences, Hakemli Üniversite Dergisi, Ulusal, 2018, cilt 1, ss 22-38
Özet
<p class="MsoNormal" style="margin-top:6.0pt;margin-right:0cm;margin-bottom:6.0pt; margin-left:0cm;text-align:justify;text-justify:inter-ideograph;mso-line-height-alt: 6.0pt"><span style="font-size:8.0pt;font-family:"Cambria","serif"">Biodegradable implants have many advantages over conventional steel and titanium based implants. Most important of these is the ability of these implants to degrade within a desired span of time (compatible with tissue and bone growth) after their function is over, without giving any harm to the body.</span><b><span lang="EN-US" style="font-size:10.0pt; font-family:"Cambria","serif";mso-fareast-font-family:"Times New Roman"; mso-bidi-font-family:Arial;mso-ansi-language:EN-US"><o:p></o:p></span></b></p><p class="MsoNormal" style="margin-bottom:6.0pt;text-align:justify;text-justify: inter-ideograph;mso-line-height-alt:6.0pt"><span style="font-size:8.0pt; font-family:"Cambria","serif"">The aim of this study is to develop a magnesium based biodegradable implant to be used as a bone plate. Mechanical and physical properties of Mg alloys that should possess for these applications are almost completely established, whereas the applicability still has to be investigated.<o:p></o:p></span></p><p class="MsoNormal" style="margin-bottom:6.0pt;text-align:justify;text-justify: inter-ideograph;mso-line-height-alt:6.0pt"><span style="font-size:8.0pt; font-family:"Cambria","serif";mso-bidi-font-weight:bold">In this study, Mg/MgZn/Zn composites produced by mechanical alloying and hot pressing. </span><span style="font-size:8.0pt;font-family:"Cambria","serif"">Biodegradability of Mg/MgZn/Zn composites was tested as in-vitro in SBF solution. SBF (simulated body fluid) is nearly equal to human body blood plasma with ion concentrations. <o:p></o:p></span></p><p class="MsoNormal" style="margin-bottom:6.0pt;text-align:justify;text-justify: inter-ideograph;mso-line-height-alt:6.0pt"><span style="font-size:8.0pt; font-family:"Cambria","serif"">Seven implants were produced. They were placed in SBF solution and then their corrosion resistances were followed. </span><span lang="EN-US" style="font-size:8.0pt;font-family:"Cambria","serif";mso-ansi-language: EN-US">During the process, visual changes of the implants were observed, pH, Mg ion concentrations of SBF solutions and mass, dimensional changes of degraded implants in solutions were measured. As soon as, implants were placed in SBF solutions, gas outlet of H<sub>2 </sub>was observed, because of Redox reaction, which took place between implants and SBF. <o:p></o:p></span></p><p> </p><p class="MsoNormal" style="margin-bottom:6.0pt;text-align:justify;text-justify: inter-ideograph;mso-line-height-alt:6.0pt"><span style="font-size:8.0pt; font-family:"Cambria","serif"">The composites in SBF remained between 1-360 hours and Zn% 2.35 and 3.10 had the longest degradation time when compared to others. Therefore only three of the composites Zn% 0 (7h), 2.35 (360h) and 3.10 (192h) were selected for the further, SEM and mechanical control tests.<o:p></o:p></span></p>