Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E-2 and prostaglandin F2 alpha and clinical parameters of chronic periodontitis

Makaleler > Tam Makale · 2003

Yazarlar: S VARDAR, H BAYLAS, Afig BERDELİ

JOURNAL OF PERIODONTOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2003, cilt 74, ss 57-63

DOI: 10.1902/jop.2003.74.1.57

Özet

Background: The purpose of the present study was to evaluate the effect of a relatively selective cyclooxygenase (COX)-2 inhibitor (nimesulide) and non-selective COX-1/COX-2 inhibitor (naproxen) used as an adjunct to non-surgical (scaling and root planing [SRP]) periodontal therapy in chronic periodontitis patients on the gingival tissue (GT) levels of prostaglandin (PG)E-2 and PGF(2alpha).

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