Retrospective, Single-Center Evaluation of Liver Cirrhosis Cases in a Geriatric Population

Articles > Article · 2020

Authors: Aslı KILAVUZ, FERİT ÇELİK, Nalan Gülşen ÜNAL, Ali ŞENKAYA, Seymur ASLANOV, Emine Sumru SAVAŞ, Fatih TEKİN, Ahmet Ömer ÖZÜTEMİZ

Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, Refereed Journals of Other Institutions, International, Scopus, 2020, vol 34, pp 93-101

DOI: 10.5505/deutfd.2020.65365

Summary

<p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">Objective: Since there is insufficient epidemiological data on liver cirrhosis, especially in the elderly population of many countries, we aimed to evaluate geriatric cases with liver cirrhosis hospitalized at our gastroenterology clinic, retrospectively.</span></font></p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">Materials and Methods: The study included 99 patients aged 65 years and over who were hospitalized with liver cirrhosis in Ege University Faculty of Medicine, department of gastroenterology. The socio-demographic, clinical and laboratory data were recorded from the patient files.</span></font></p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">Results: In total, 99 elderly patients (mean age 71.7 ± 5.2 years; 59% male) were included. Hepatocellular carcinoma was statistically significantly correlated with etiology, presence of ascites, the Model of End-Stage Liver Disease score and the Child-Turcotte-Pugh score (p=0.003, p=0.009, p=0.033, p=0.003, respectively).</span></font></p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">The presence of esophageal varices was statistically significantly correlated with class and scores of the Child-Turcotte-Pugh, total bilirubin, Model of End-Stage Liver Disease score and the presence of ascites (p&lt; 0.0001, p=0.001, p=0.011, p=0.004, p=0.004, respectively).</span></font></p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">Conclusion: The main etiology of liver cirrhosis was Hepatitis C virus, which accounted for almost one-third of the cirrhotic elderly inpatients at the gastroenterology department. Hepatocellular carsinoma was the leading cause of hospitalization. Elderly patients with liver cirrhosis should be carefully evaluated for cirrhosis complications. The Child-Turcotte-Pugh classification and</span></font></p><p class="p1" style="margin-bottom: 0px; font-variant-numeric: normal; font-variant-east-asian: normal; font-stretch: normal; line-height: normal;"><font color="#244061" face="Times"><span style="font-size: 8.5px;">Model of End-Stage Liver Disease scoring should be undertaken, and the suitability for liver transplantation should be considered in the follow-up and treatment of this patients.</span></font></p>

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