Novel Schiff base-Pt(ii) complexes: inhibition of Aβ aggregation via histidine interaction

Articles > Article · 2025

Authors: Salih GÜNNAZ

NEW JOURNAL OF CHEMISTRY, Journal Indexed in SCI Expanded, International, Scopus, 2025, vol 1, pp 1-14

DOI: 10.1039/D5NJ04180E

Summary

Three novel Schiff base–Pt( ii ) complexes were synthesized and characterized. Complexes I and III showed significant anti-amyloid activity by inhibiting Aβ 1–42 peptide aggregation in vitro , with potential to cross the blood–brain barrier.

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