PTPN22 gene polymorphism in Takayasus arteritis
Articles > Article · 2008
Authors: N. Sahin, Kenan AKSU, S. Kamali, M. Bicakcigil, Z. OEZBALKAN, I. Fresko, H. Oezer, S. Akar, A. M. Onat, V. Cobankara, S. Kiraz, M. A. Oeztuerk, E. Tunc, E. Yuecel, A. ATES, Gökhan KESER, M. Inanc, H. Direskeneli, G. Saruhan-Direskeneli
RHEUMATOLOGY, Journal Indexed in SCI Expanded, International, 2008, vol 47, pp 634-635
DOI: 10.1093/rheumatology/ken106
Summary
Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.