PTPN22 gene polymorphism in Takayasus arteritis
Makaleler > Tam Makale · 2008
Yazarlar: N. Sahin, Kenan AKSU, S. Kamali, M. Bicakcigil, Z. OEZBALKAN, I. Fresko, H. Oezer, S. Akar, A. M. Onat, V. Cobankara, S. Kiraz, M. A. Oeztuerk, E. Tunc, E. Yuecel, A. ATES, Gökhan KESER, M. Inanc, H. Direskeneli, G. Saruhan-Direskeneli
RHEUMATOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2008, cilt 47, ss 634-635
DOI: 10.1093/rheumatology/ken106
Özet
Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.