Lignans, alkaloids and coumarins from Haplophyllum vulcanicum
Articles > Article ยท 1996
Authors: B GOZLER, D RENTSCH, T GOZLER, Nehir SOMER, M HESSE
Phytochemistry, Journal Indexed in SCI Expanded, International, 1996, vol 42, pp 695-699
DOI: 10.1016/0031-9422(96)00062-3
Summary
Six lignans, (-)-haplomyrfolol, (-)-haplomyrfolin, (-)-kusunokinin, (-)-syringaresinol, diphyllin and (-)-tuberculatin, five furoquinoline alkaloids, dictamnine, gamma-fagarine, haplopine, robustine and skimmianine, and two coumarins, scopoletin and umbelliferone, have been isolated from Haplophyllum vulcanicum. (-)-Haplomyrfolol, a novel dibenzylbutyrolactol, exists as an epimeric mixture in solution. Complete assignments of the proton and carbon chemical shifts for the individual epimers were accomplished on the basis of high resolution 1D and 2D NMR data. This is the first report of (-)-syringaresinol from the genus Haplophyllum and of (-)-haplomyrfolin, (-)-tuberculatin, dictamnine, haplopine and umbelliferone from the title species.