Phyto-Niosomes:In VitroAssessment of the Novel Nanovesicles Containing Marigold Extract
Articles > Article · 2015
Authors: Rabia Nur ÜN, F. Baris BARLAS, Murat Yavuz, Didem Ag SELECI, Muharrem SELECI, Zinar Pınar GÜMÜŞ, Emine GÜLER ÇELİK, Bilal Demir, Mustafa Can, Hakan COŞKUNOL, Suna TİMUR
International Journal of Polymeric Materials and Polymeric Biomaterials, Journal Indexed in SCI Expanded, International, WoS, 2015, vol 64, pp 927-937
DOI: 10.1080/00914037.2015.1030663
Summary
Herbal compounds, so-called phytoconstituents, illustrate poor absorption by living cells. Phytosomes are advanced form of herbal compounds that show higher absorption rate and bioavailability, which results better than conventional plant extracts. Niosomes, which are made of nonionic surfactants, create better chemical and stability conditions besides lipid vesicles. This study covers the preparation, characterization and cell culture applications of phyto-niosomes of Marigold extract. Before the encapsulation process, extracts of selected plants were prepared and the extract that presents best bioactivity was chosen. The resulting phyto-niosomes were characterized and their biological activities including cytotoxicity, wound healing and antioxidant activity were investigated.