The Impact of Surgical Staging on the Prognosis of Mucinous Borderline Tumors of the Ovaries: A Multicenter Study
Makaleler > Tam Makale · 2017
Yazarlar: Kemal GUNGORDUK, Osman ASICIOGLU, Elena Ioana BRAICU, Jumana ALMUHEIMID, Sevki Goksun GOKULU, Nilufer CETINKAYA, Tayfun GUNGOR, Gonca PAKAY, Elcin Uzmez Telli, Zeliha Firat CUYLAN, Tayfun Toptas, Ahmet BILGI, Ramazan OZYURT, Elif Agacayak, Aykut OZDEMIR, Nuri YILDIRIM, Salih Taskin, Tufan Oge, Onur EROL, Levent AKMAN, Anil Turan, Mehmet Sait Icen, Taylan SENOL, Ozlem Irak Ovali, Burcu Yucesoy, Ozgu GUNGORDUK, Osman TEMIZKAN, Muzaffer SANCI, Tayup Simsek, Mehmet Mutlu MEYDANLI, Mehmet Harma, Levent YASAR, Aysel Derbent UYSAL, Ates KARATEKE, Firat Ortac, Sabit Sinan Ozalp, Jalid SEHOULI, Mustafa Zelal MUALLEM
Anticancer Research, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2017, cilt 37, ss 5609-5616
DOI: 10.21873/anticanres.11995
Özet
BACKGROUND/AIM: The purpose of this study was to prove the effect of complete surgical staging of patients with mucinous borderline ovarian tumors (mBOTs) especially appendectomy on progression-free survival (PFS) and overall survival (OS). PATIENTS AND METHODS: The database of 14 gynecological oncology departments from Turkey and Germany were comprehensively searched for women who underwent primary surgery for an ovarian tumor between January 1, 1998, and December 31, 2015, and whose final diagnosis was mBOT. RESULTS: A total of 364 patients with mBOT with a median age of 43.1 years were included in this analysis. The median OS of all patients was 53.1 months. The majority of cases had Stage IA (78.6%). In univariate and multivariate analyses, radical surgery, omentectomy, appendectomy, lymphadenectomy, and adding adjuvant chemotherapy were not independent prognostic factors for PFS and OS. Furthermore, FIGO stage (≥IC vs. <IC), radical surgery, and staging surgery were not independent risk factors for recurrence of mBOTs. Finally, abnormal macroscopic appendix and FIGO stage (≥IC vs.