Labeling of ornidazole with iodine-131
Articles > Article · 1998
Authors: MAKBULE AŞIKOĞLU, Fatma YURT, Perihan ÜNAK
Journal of Radioanalytical and Nuclear Chemistry, Journal Indexed in SCI Expanded, International, WoS, 1998, vol 237, pp 143-145
DOI: 10.1007/bf02386678
Summary
Ornidazole (1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole) was labeled with iodine-131 by using iodogen method. Quality controls were performed by instant thin layer chromatography (ITLC) and electrophoresis methods. Labeling yield was 91%. Iodination was carried out by substitution of chloride by iodine-131. Structure was confirmed by H-1-NMR.