Investigation of maternal melatonin effect on the hippocampal formation of newborn rat model of intrauterine cortical dysplasia
Makaleler > Tam Makale · 2010
Yazarlar: MERAL BAKA, Yiğit UYANIKGİL, Utku Ateş, NİLGÜN KÜLTÜRSAY
CHILDS NERVOUS SYSTEM, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 26, ss 1575-1581
DOI: 10.1007/s00381-010-1147-5
Özet
Objectives Cortical dysplasia is a cortical malformation resulting from any developmental defects during different periods of development. This study aims to investigate the hippocampal histopathological alterations in the neonates with cortical dysplasia due to the prenatal exposure to carmustine (1,3-bis (2-chloroethyl)-1-nitrosoure; BCNU) and the possible effects of prophylaxis with melatonin, a neuroprotective agent.