Retrospective analysis of hysteroscopic findings in breast cancer patients having adjuvant tamoxifen treatment.
Articles > Article · 2010
Authors: Fatih ŞENDAĞ, Çağdaş ŞAHİN, B Zeybek, M Cosan Terek, K Oztekin, O Bilgin
European journal of gynaecological oncology, International, 2010, vol 31, pp 415-7
Summary
PURPOSE OF INVESTIGATION: To evaluate the effects of tamoxifen on the endometrium of breast cancer patients by hysteroscopy and endometrial sampling. METHODS: Thirty-seven breast cancer patients using tamoxifen underwent hysteroscopy because of postmenopausal endometrial thickening or abnormal uterine bleeding. Hysteroscopic findings were compared with histopathology and ultrasonographic measurement of the endometrium. RESULTS: Nineteen women showed endometrial abnormalities (51%) out of 37 patients. Negative and positive predictive values for hysteroscopy in detecting endometrial abnormalities were 100% and 94%, respectively. CONCLUSION: Endometrial surveillance is an important part of gynecological follow-up in breast cancer patients using tamoxifen and the liberal use of hysteroscopy aids in the diagnosis of abnormal endometrium.