Novel Schiff base-Pt( ii ) complexes: inhibition of Aβ aggregation via histidine interaction
Makaleler > Tam Makale · 2026
Yazarlar: Sevil İRİŞLİ, UMUT DOĞAN, Salih GÜNNAZ, Fatma YURT, ONUR ŞAHİN
NEW JOURNAL OF CHEMISTRY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2026, cilt 50, ss 1125-1138
DOI: 10.1039/d5nj04180e
Özet
Three novel Schiff base–Pt( ii ) complexes were synthesized and characterized. Complexes I and III showed significant anti-amyloid activity by inhibiting Aβ 1–42 peptide aggregation in vitro , with potential to cross the blood–brain barrier.