Food and Drug Interactions: A General Review
Makaleler > Tam Makale · 2014
Yazarlar: Semih ÖTLEŞ, A Senturk
Acta Scientiarum Polonorum Technologia Alimentaria, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2014, cilt 13, ss 89-102
Özet
Medications are used commonly to treat acute and chronic illness.Many people can obtain new drugs improved by research and novel technology [Bobroff et al. 2009].Medications should have some important attributes in general.They should be extremely specifi c in their effects, have the same predictable effect for all patients, never be affected by concomitant food or other medications, exhibit linear potency, be totally non-toxic in any dosage and require only a single dose to affect a permanent cure [Bushra et al. 2011].Medications could help people to live more healthy.Although medicines are often prescribed, it is important to realise that they must still be used with caution [Bobroff et al. 2009].There are too many potential drug-nutrient interactions (DNIs) due to the widespread use of patent medicines along with the broad variability in nutrition status, dietary habits, food composition, and dietary supplement use [Boullata and Hudson 2012].Drug--nutrient interaction is defi ned as an alteration of kinetics or dynamics of a drug or a nutritional element, or a compromise in nutritional status as a result of the addition of a drug [Braun 2012].Another comprehensive defi nition of drug-nutrient interaction is that it is an interaction resulting from a physical, chemical, physiologic, or pathophysiologic relationship between a drug and a nutrient, multiple nutrients, food in general, or nutritional status [Boullata 2010].Concurrent use of drugs increases the chance of drug interactions, but no-one knows what the interactions of all these drugs are.However, research on drug-nutrient interactions is very limited and further research is needed in some cases, to check the fi ndings.Research trials may produce confl icting information and sometimes the research has been carried out into