Cycloartane-type glycosides from Astragalus amblolepis
Articles > Article · 2009
Authors: Emre Polat, Özgen ALANKUŞ, Angela Perrone, Sonia Piacente, ERDAL BEDİR
PHYTOCHEMISTRY, Journal Indexed in SCI Expanded, International, 2009, vol 70, pp 628-634
DOI: 10.1016/j.phytochem.2009.03.006
Summary
Five cycloartane-type triterpene glycosides were isolated from the methanol extract of the roots of Astragalus amblolepis Fischer along with one known saponin, 3-O-beta-D-xylopyranosyl-16-O-beta-D-glucopyranosyl-3 beta,6 alpha,16 beta,24(S),25-pentahydroxy-cycloartane. Structures of the compounds were established as 3-O-beta-D-xylopyranosyl-25-O-beta-D-glucopyranosyl-3 beta,6 alpha,16 beta,24(S),25-pentahydroxy-cycloartane, 3-O-[beta-D-glucuronopyranosyl-(1 -> 2)-beta-D-xylopyranosyl]-25-O-beta-D-glucopyranosyl-3 beta,6 alpha, 16 beta,24(S),25-pentahydroxy-cycloartane, 3-O-beta-D-xylopyranosyl-24,25-di-O-beta-D-glucopyranosyl-3 beta,6 alpha,16 beta,24(S),25-pentahydroxy-cycloartane, 6-O-alpha-L-rhamnopyranosyl-16,24-di-O-beta-D-glucopyranosyl-3 beta, 6 alpha,16 beta,24(S),25-pentahydroxy-cycloartane, 6-O-alpha-L-rhamnopyranosyl-16,25-di-O-beta-D-glucopyranosyl-3 beta,6 alpha, 16 beta,24(S),25-pentahydroxy-cycloartane by using 1D and 2D-NMR techniques and mass spectrometry. To the best of our knowledge, the glucuronic acid moiety in cycloartanes is reported for the first time. (C) 2009 Elsevier Ltd. All rights reserved.