The Detrimental Effects of Diabetes on Pluripotency Determined by KLF4, SOX2, C-MYC and OCT4 Immunoreactivity in Rat Testes
Articles > Article · 2013
Authors: Hüseyin AKTUĞ, Ayşegül UYSAL, Altuğ YAVAŞOĞLU, Fatih OLTULU, Saadet O. AKARCA, Özlem YILMAZ, Gülperi ÖKTEM
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, Journal Indexed in SCI Expanded, International, 2013, vol 22, pp 327-335
Summary
Background. Diabetes mellitus (DM) is a multisystem disorder. Type 1 DM can be experimentally induced in rats with streptozotocin (STZ). Diabetic conditions result in testicular oxidative stress and suppressed male reproductive activity as well as decreases in both testicular organ weights and subject weights.