The prevalence of RET/PTC mutations in papillary thyroid cancers in Turkish population and its relation between tumor histopathology and prognostic factors
Makaleler > Tam Makale · 2008
Yazarlar: Mehmet ERDOĞAN, Afig BERDELİ, MUAMMER KARADENİZ, Yeşim ERTAN, Şevki ÇETİNKALP, Lütfiye Füsun SAYGILI, MÜGE TUNÇYÜREK, CENGİZ YILMAZ, MEHMET TÜZÜN, TAYLAN KABALAK, Hatice ULUER, A. G. Ozgen
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2008, cilt 116, ss 225-230
Özet
Objective: In recent years, thyroid cancer has been at the forefront of molecular pathology as a result of the consequences of the Chernobyl disaster and the recognition of the role of RET/PTC rearrangements in papillary thyroid carcinomas (PTCs). Correlation of RET/PTC expression with clinical outcome is controversial. This study aims to identify the prevalence of RET/PTC oncogene expression in Turkey, and to investigate the correlation between RET/PTC oncogene expression and the known prognostic factors of PTC in 101 patients.