Mannose-binding lectin may affect pregnancy outcome
Articles > Article · 2015
Authors: Sebnem CALKAVUR, Gulin ERDEMIR, HÜSEYİN ONAY, Özge ALTUN, Mehmet YALAZ, Osman ZEKİOĞLU, Güzide AKSU, Feriştah Ferda ÖZKINAY, Fuat AKERCAN, NİLGÜN KÜLTÜRSAY
TURKISH JOURNAL OF PEDIATRICS, Journal Indexed in SCI Expanded, International, 2015, vol 57, pp 26-33
Summary
Mannose-binding lectin (MBL) is a component of the innate immune system and acts as a complement activator through the lectin pathway. Genetic variations of MBL and low MBL levels cause several infection problems, which may also be related to pregnancy problems. We aimed to investigate the role of MBL gene codon 54 polymorphism and serum MBL levels in pregnancy problems and premature delivery.