Regulation of matrix metalloproteinases-8, -9 and endogenous tissue inhibitor-1 in oral biofluids during pregnancy and postpartum
Articles > Article · 2021
Authors: V Özgen Öztürk, Pınar MERİÇ KANTAR, Timo Sorsa, Taina Tervahartiala, Nagihan Bostanci, Solomon O Nwhator, Gülnur EMİNGİL
Archives of Oral Biology, Journal Indexed in SCI Expanded, International, WoS, 2021, vol 124, pp 105065-105065
DOI: 10.1016/j.archoralbio.2021.105065
Summary
Objective: During pregnancy, mothers undergoe considerable physiological changes affecting the whole body including periodontal tissues. Susceptibility to gingival inflammation during pregnancy could be mediated by modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). Therefore, the aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMPs and TIMPs during the second and third trimester of pregnancy and postpartum.