Regulation of matrix metalloproteinases-8, -9 and endogenous tissue inhibitor-1 in oral biofluids during pregnancy and postpartum

Articles > Article · 2021

Authors: V Özgen Öztürk, Pınar MERİÇ KANTAR, Timo Sorsa, Taina Tervahartiala, Nagihan Bostanci, Solomon O Nwhator, Gülnur EMİNGİL

Archives of Oral Biology, Journal Indexed in SCI Expanded, International, WoS, 2021, vol 124, pp 105065-105065

DOI: 10.1016/j.archoralbio.2021.105065

Summary

Objective: During pregnancy, mothers undergoe considerable physiological changes affecting the whole body including periodontal tissues. Susceptibility to gingival inflammation during pregnancy could be mediated by modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). Therefore, the aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMPs and TIMPs during the second and third trimester of pregnancy and postpartum.

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