Inhibition of renin-angiotensin system in experimental acute pancreatitis in rats: A new therapeutic target?
Makaleler > Tam Makale · 2010
Yazarlar: Nevin ORUÇ, Ahmet Ömer ÖZÜTEMİZ, Deniz NART, Gul YÜCE, Handan AK, Tankut Ilter
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 62, ss 353-360
DOI: 10.1016/j.etp.2009.05.001
Özet
Objective: Pancreatic renin-angiotensin system has been implied to play a role in the regulation of pancreatic functions and could be a new therapeutic target in acute pancreatitis. The aim of this study was to evaluate the therapeutic potential of angiotensin-converting-enzyme inhibition by captopril and angiotensin II type 1 receptor inhibition by L-158809 and losartan experimentally in acute pancreatitis.