Genetic aspects of dental caries
Articles > Article · 2022
Authors: Dilşah ÇOĞULU, Ceren Sağlam
Frontiers in Dental Medicine, Refereed Journals of Other Institutions, International, Scopus, 2022, vol 3, pp 1-5
DOI: 10.3389/fdmed.2022.1060177
Summary
Dental caries is a common chronic disease affecting humans in all age groups. Various factors can affect the formation of caries including demineralization and remineralization processes with oral flora; dietary and oral hygiene habits; salivary composition, flow rate, pH and buffering capacity; morphological features of the teeth; fluoride exposure; and environmental and socioeconomic factors. One of the most important factors causing inter-individual variations in caries susceptibility is the host genetics. Several genes affect individual caries susceptibility. Genes play a role in immune response, development of saliva and tooth enamel. The present review aims to overview the literature focusing on the genetic features of dental caries.