Antimicrobial Triterpenoid Glycosides from Cephalaria scoparia
Makaleler > Tam Makale · 2010
Yazarlar: Nazlı SARIKAHYA, Sueheyla Kirmiziguel
Journal of Natural Products, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2010, cilt 73, ss 825-830
DOI: 10.1021/np900724u
Özet
Five new oleanane-type triterpenoid glycosides (1-5), named scoposides A-E, along with one known bisdesmosidic triterpene glycoside, were isolated from the aerial parts of Cephalaria scoparia. Three prosapogenins (2a-4a) were also obtained after alkaline hydrolysis of the bisdesmosidic compounds 2-4. The structures of compounds 1-5 were determined by spectroscopic (1D and 2D NMR, HRESIMS) and chemical methods. The antimicrobial effects of compounds 1-5 were evaluated against a small panel of Gram-positive and Gram-negative bacteria.