Stiff Person Syndrome-The Less Common Antibody: A Case Report

Makaleler > Tam Makale · 2020

Yazarlar: HÜSEYİN NEZİH ÖZDEMİR, Derya YÖNDEM, SEREN KAPLAN ÖZDEMİR, Figen GÖKÇAY

Turkish Journal Of Neurology, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2020, cilt 26, ss 39-41

DOI: 10.4274/tnd.galenos.2019.80708

Özet

Stiff Person syndrome (SPS) is a rare, disabling syndrome characterized by progressive muscle stiffness and axial rigidity.It may have an autoimmune, paraneoplastic or cryptogenic etiology.A 59-year-old woman presented with stiffness and involuntary spasms in the lower extremities.In a neurologic examination, lower extremity and axial rigidity were revealed.Anti-glutamic acid decarboxylase antibody was negative, anti-amphiphysin was antibody positive.She was diagnosed as having SPS.The symptoms were improved after intravenous immunoglobulin and cancer therapy.

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