A novel multicomponent grading system for obstructive sleep apnoea severity applied in the ESADA cohort
Bildiriler > Özet Bildiri
Yazarlar: Winfried Randerath, Simon Herkenrath, Marcel Treml, Ludger Grote, Jan Hedner, Maria R Bonsignore, Jean-Louis Pépin, Silke Ryan, Sofia Schiza, Johan Verbraecken, Walter T Mcnicholas, Athanasia Pataka, Pawel Sliwinski, Özen KAÇMAZ BAŞOĞLU
Sleep and control of breathing, , , Uluslararası, Özet Bildiri, ss 2516-2516
DOI: 10.1183/13993003.congress-2020.2516
Özet
Background: A novel multicomponent grading system for obstructive sleep apnoea (OSA) severity has been proposed. It includes symptom burden and end-organ impact to classify patients in four groups (“Baveno classification”*). The current study applied this classification in a large representative patient cohort. Methods: OSA patients from the European Sleep Apnoea Data Base (ESADA) cohort, collected from 2007 onwards in 20 countries were categorized according to symptoms (Epworth Sleepiness Scale Score ≥9, subjective sleep length ≥11h, diagnosis of insomnia) and major end-organ impact (uncontrolled arterial hypertension, atrial fibrillation, heart failure, diabetes, and history of stroke). Results: 14499 patients (28% female, 54±12 years, BMI 33±7 kg/m²) were categorized. Each Baveno class comprised a relevant proportion of patients. The percentage sleep time with oxygen saturation below 90% (T90) was elevated in patients with either severe symptoms or major end-organ impact and even further increased if both conditions coincided (table 1). Conclusion: Our data show that the four suggested OSA phenotypes of the “Baveno” classification reflect clinical phenotypes in a large, representative European patient cohort. The impact of T90, known to be correlated with poor cognitive, cardiovascular and metabolic outcomes, may indicate the prognostic relevance of the grading system. * Randerath et al. ERJ 2018; 52: 1702616