A Novel Glycoside from Acanthus hirsutus (Acanthaceae)

Makaleler > Tam Makale · 2010

Yazarlar: Seval CAPANLAR, Nazlı SARIKAHYA, İhsan YAŞA, SÜHEYLA KIRMIZIGÜL

NATURAL PRODUCT COMMUNICATIONS, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 5, ss 563-566

Özet

A novel glycoside, hirsutusoide (1), characterized as 2-(o-hydroxyphenyl)-2-hydroxyethenyl-O-beta-glucopyranoside, was isolated from the endemic Acanthus hirsutus Boiss. In addition to compound 1, three known glycosides, luteolin-7-O-beta-D-glucuronide (2), beta-sitosterol-3-O-beta-D-glucopyranoside (3) and (2R)-2-O-beta-D-glucopyranosyl-2H-1,4-benzoxazin-3(4H)-one (4), were also isolated. Compound 2 was the first report from this genus. Antimicrobial and antioxidant activity of the extracts and the novel compound were investigated by determining MIC (mu g/mL) and IC50 (mu g/mL) values, respectively.

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