Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD

Articles > Article ยท 2016

Authors: Abdullah SAYINER, Jadwiga A. Wedzicha, Donald Banerji, Kenneth R. Chapman, Jorgen Vestbo, Nicolas Roche, Timothy Ayers, Chau Thach, Robert Fogel, Francesco Patalano, Claus F. Vogelmeier

NEW ENGLAND JOURNAL OF MEDICINE, Journal Indexed in SCI Expanded, International, 2016, vol 374, pp 2222-2234

DOI: 10.1056/nejmoa1516385

Summary

BACKGROUND Most guidelines recommend either a long-acting beta-agonist (LABA) plus an inhaled glucocorticoid or a long-acting muscarinic antagonist (LAMA) as the first-choice treatment for patients with chronic obstructive pulmonary disease (COPD) who have a high risk of exacerbations. The role of treatment with a LABA-LAMA regimen in these patients is unclear.

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