Pregnancy-associated osteoporosis presenting severe vertebral fractures
Articles > Article · 2013
Authors: CİHAT ÖZTÜRK, Funda ÇALIŞ, Halil AKKURT, Yeşim AKKOÇ
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, Journal Indexed in SCI Expanded, International, 2013, vol 40, pp 288-292
DOI: 10.1111/jog.12157
Summary
The syndrome of pregnancy-associated osteoporosis (PAO) is a rare disorder which occurs either in late pregnancy or early post-partum period leading to fragility fracture(s), most commonly in the vertebral bodies. We presented two cases with PAO who had compression fractures at multiple levels involving five vertebrae in one case and 10 vertebrae in the other. Their spinal bone mineral density values were below -2.5 standard deviations. Anti-osteoporotic treatments with nasal calcitonin 400IU/day, vitamin D 300.000IU single dose, calcium 1000mg/day, vitamin D 880IU/day were initiated. In one case, kyphoplasty was performed by a spinal surgeon. In addition to a thoracolumbosacral orthosis, a rehabilitation program including muscle strengthening, range of motion, relaxation and weight-bearing exercises was started for both cases. These cases emphasize that all pregnant women with complaints of back/lumbar pain should be carefully evaluated.