Immune status and autoantibody formation in children with chronic hepatitis B infection
Articles > Article · 2002
Authors: F UNAL, F GENEL, F OZGENC, Güzide AKSU, S AYDOGDU, Necil KÜTÜKÇÜLER, RV YAĞCI
PANMINERVA MEDICA, Journal Indexed in SCI Expanded, International, 2002, vol 44, pp 353-357
Summary
Background. The hepatitis B virus (HBV) causes a wide spectrum of disease which ranges from acute hepatitis to liver cirrhosis. Patients who fail to mount a vigorous immune response in acute HBV develop chronic infection. Therefore, the aim of the study was to determine the cellular and humoral immune parameters of the patients with chronic HBV and to evaluate the prevalence of autoantibodies before the beginning of immunomodulator and antiviral therapy.